Methotrexate (DMARDs) is used to treat which condition?

Methotrexate (DMARDs) is used to treat which condition?

• A. Hypertension
• B. Diabetes
• C. Asthma
• D. Rheumatoid arthritis

Answer: (D)

Methotrexate, used in low doses as a disease-modifying antirheumatic drug, is a cornerstone therapy for rheumatoid arthritis. In RA, the immune system drives joint inflammation and progressive damage; DMARDs slow this process, reducing inflammation and joint erosion over time and improving function. Methotrexate works by dampening immune cell activity and increasing anti-inflammatory adenosine, helping to control the autoimmune attack on joints. It’s not a standard treatment for hypertension, diabetes, or asthma, which are managed with other classes of medications. So the condition best treated by methotrexate in this context is rheumatoid arthritis.

Methotrexate, used in low doses as a disease-modifying antirheumatic drug, is a cornerstone therapy for rheumatoid arthritis. In RA, the immune system drives joint inflammation and progressive damage; DMARDs slow this process, reducing inflammation and joint erosion over time and improving function. Methotrexate works by dampening immune cell activity and increasing anti-inflammatory adenosine, helping to control the autoimmune attack on joints. It’s not a standard treatment for hypertension, diabetes, or asthma, which are managed with other classes of medications. So the condition best treated by methotrexate in this context is rheumatoid arthritis.